Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027942 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL24027895 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL12577688 | 0.84 | ERN1 (0.43) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL24027926 | 0.84 | ERN1 (0.47) | ALDH1A1TDP1ERN1TLR2TLR1 | |
| SCHEMBL30212834 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL18359658 | 0.76 | ERN1 (0.55) | ERN1 | |
| SCHEMBL1570740 | 0.76 | ALDH1A1 (0.72) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL31469616 | 0.76 | ALDH1A1 (0.72) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL27753912 | 0.76 | ALDH1A1 (0.72) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL30011114 | 0.76 | FFAR1 (0.42) | ALDH1A1KDM4ETDP1DHFRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697974-A | Imidazole 3-oxide derivative based ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2023-02-03 | — | — | CN | disclosed |