Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524412 | 0.94 | MEN1 (0.49) | GPR119MEN1KMT2AKCNH2HRH3 | |
| SCHEMBL2429206 | 0.94 | MEN1 (0.49) | GPR119MEN1KMT2AKCNH2HRH3 | |
| SCHEMBL7387197 | 0.83 | CHEK2 (0.46) | GPR119MEN1KMT2ANPSR1 | |
| SCHEMBL5151622 | 0.82 | NPC1 (0.47) | GPR119MAPT | |
| SCHEMBL14500062 | 0.82 | KMT2A (0.39) | GPR119MEN1KMT2AKCNH2HRH3 | |
| SCHEMBL13437495 | 0.82 | TDP1 (0.41) | GPR119MEN1KMT2AKCNH2HRH3 | |
| SCHEMBL7398730 | 0.82 | CHEK2 (0.57) | GPR119MEN1KMT2AKCNH2HRH3 | |
| SCHEMBL30213365 | 0.82 | MEN1 (0.45) | GPR119MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14592667 | 0.81 | GPR119 (0.52) | GPR119MAPTNPSR1ATM | |
| SCHEMBL7366249 | 0.80 | CHEK2 (0.58) | GPR119MAPTNPSR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768768-A | Galectin-3 inhibitors | 百时美施贵宝公司 | 2023-03-07 | — | — | CN | disclosed |