Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.68 |
| ▸ | CSNK1A1 | P48729 | 8/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30213389 | 0.85 | MAPK14 (0.51) | CRBNCSNK1A1MAPK14ACHEMEN1 | |
| SCHEMBL30213204 | 0.82 | CRBN (0.50) | CRBNCSNK1A1MEN1KMT2AIKZF2 | |
| SCHEMBL24078841 | 0.82 | CRBN (0.50) | CRBNCSNK1A1MEN1KMT2AIKZF2 | |
| SCHEMBL24745571 | 0.82 | CRBN (0.56) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL27387190 | 0.81 | CRBN (1.00) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL30213383 | 0.79 | CRBN (0.47) | CRBNCSNK1A1MAPK14ACHEMEN1 | |
| SCHEMBL29126565 | 0.78 | CRBN (0.44) | CRBNCSNK1A1NPC1RAB9AIKZF2 | |
| SCHEMBL824532 | 0.77 | CRBN (0.63) | CRBNKMT2ANPC1RAB9A | |
| SCHEMBL30121132 | 0.77 | CRBN (0.63) | CRBNKMT2ANPC1RAB9A | |
| SCHEMBL24319166 | 0.76 | CRBN (0.60) | CRBNCSNK1A1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768768-A | Galectin-3 inhibitors | 百时美施贵宝公司 | 2023-03-07 | — | — | CN | disclosed |