Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 10/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30213389 | 0.86 | MAPK14 (0.51) | CRBNCSNK1A1IKZF2MEN1KMT2A | |
| SCHEMBL30213320 | 0.86 | CRBN (0.65) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL24078841 | 0.86 | CRBN (0.50) | CRBNCSNK1A1IKZF2MEN1KMT2A | |
| SCHEMBL30213204 | 0.86 | CRBN (0.50) | CRBNCSNK1A1IKZF2MEN1KMT2A | |
| SCHEMBL30213434 | 0.80 | CRBN (0.56) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30213359 | 0.79 | CRBN (0.68) | CRBNCSNK1A1IKZF2MEN1KMT2A | |
| SCHEMBL30213409 | 0.74 | CRBN (0.68) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30213232 | 0.73 | CRBN (0.73) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL29126565 | 0.73 | CRBN (0.44) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL30341612 | 0.73 | CRBN (0.44) | CRBNCSNK1A1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768768-A | Galectin-3 inhibitors | 百时美施贵宝公司 | 2023-03-07 | — | — | CN | disclosed |