Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 11/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.44 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744480 | 0.87 | IKZF2 (0.50) | CRBNIKZF2CSNK1A1IKZF1GSPT1 | |
| SCHEMBL24319166 | 0.84 | CRBN (0.60) | CRBNIKZF2CSNK1A1DDB1 | |
| SCHEMBL23173151 | 0.83 | CRBN (0.61) | CRBNIKZF2CSNK1A1DDB1 | |
| SCHEMBL26107723 | 0.83 | CRBN (0.58) | CRBNIKZF2CSNK1A1GSPT1DDB1 | |
| SCHEMBL31347063 | 0.83 | CRBN (0.58) | CRBNIKZF2CSNK1A1GSPT1DDB1 | |
| SCHEMBL30213359 | 0.82 | CRBN (0.68) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL27097398 | 0.81 | CRBN (0.59) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL824532 | 0.80 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL30121132 | 0.80 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL26075169 | 0.79 | CRBN (0.57) | CRBNIKZF2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |