SCHEMBL30213636

SCHEMBL30213636

CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(OCC(=O)OC(C)(C)C)c1

nearest known ligand 0.86

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 19/20 0.86
FKBP5 Q13451 8/20 0.86
FKBP4 Q02790 7/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31548587 1.00 FKBP1A (0.86) FKBP1AFKBP5FKBP4
SCHEMBL18086951 1.00 FKBP1A (0.86) FKBP1AFKBP5FKBP4
SCHEMBL16298862 1.00 FKBP1A (0.86) FKBP1AFKBP5FKBP4
SCHEMBL18089279 0.95 FKBP1A (0.89) FKBP1AFKBP5FKBP4
SCHEMBL16683539 0.95 FKBP1A (0.89) FKBP1AFKBP5FKBP4
SCHEMBL13694681 0.93 FKBP1A (1.00) FKBP1AFKBP5FKBP4
SCHEMBL619873 0.93 FKBP1A (1.00) FKBP1AFKBP5FKBP4
SCHEMBL10034617 0.93 FKBP1A (0.90) FKBP1AFKBP5FKBP4
SCHEMBL619874 0.93 FKBP1A (1.00) FKBP1AFKBP5FKBP4
SCHEMBL12807412 0.93 FKBP1A (1.00) FKBP1AFKBP5FKBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12594275-B2 Immunophilin binding agents and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-07 US disclosed
US-20230063768-A1 IMMUNOPHILIN BINDING AGENTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230063768-A1 IMMUNOPHILIN BINDING AGENTS AND USES THEREOF PMP22, MAG, FABP7 FKBP1A 320/4885FKBP5 618/4885FKBP4 424/4885
US-12594275-B2 Immunophilin binding agents and uses thereof CCR1, CCRL2, CCR3 FKBP1A 1251/4885FKBP5 2845/4885FKBP4 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.