Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.84 |
| ▸ | MAOA | P21397 | 14/20 | 0.78 |
| ▸ | MAOB | P27338 | 14/20 | 0.78 |
| ▸ | STK17B | O94768 | 1/20 | 0.72 |
| ▸ | MIF | P14174 | 1/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949926 | 1.00 | CES2 (0.84) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL28949931 | 1.00 | CES2 (0.84) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL30214428 | 1.00 | CES2 (0.84) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL30214423 | 0.91 | CES2 (1.00) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL28220598 | 0.91 | CES2 (1.00) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL30214388 | 0.91 | CES2 (1.00) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL28220596 | 0.91 | CES2 (1.00) | CES2MAOAMAOBSTK17BMIF | |
| SCHEMBL18290774 | 0.88 | MAOA (1.00) | CES2MAOAMAOBMIFCYP19A1 | |
| SCHEMBL5726517 | 0.87 | MIF (0.79) | CES2MAOAMAOBMIFCYP19A1 | |
| SCHEMBL18290777 | 0.84 | MIF (0.76) | CES2MAOAMAOBMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677635-B | Orange ketone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2024-04-09 | — | — | CN | claimed |
| CN-115677635-A | Aurone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-02-03 | — | — | CN | claimed |
| CN-115677635-B | Orange ketone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2024-04-09 | — | — | CN | disclosed |
| CN-115677635-A | Aurone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-02-03 | — | — | CN | disclosed |