Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.43 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311220 | 0.90 | ALB (0.59) | ALBNAALAD2FTOMEN1MAPT | |
| SCHEMBL12914887 | 0.87 | ALB (0.62) | ALBNAALAD2FTOMEN1MAPT | |
| SCHEMBL12914888 | 0.86 | ALB (0.56) | ALBNAALAD2FTOMEN1MAPT | |
| SCHEMBL31437099 | 0.81 | KMT2A (0.56) | KMT2AMDM2TLR2 | |
| SCHEMBL3728827 | 0.81 | KMT2A (0.56) | KMT2AMDM2TLR2 | |
| SCHEMBL31437131 | 0.81 | KMT2A (0.56) | KMT2AMDM2TLR2 | |
| SCHEMBL29401421 | 0.81 | KMT2A (0.56) | KMT2AMDM2TLR2 | |
| SCHEMBL1738761 | 0.81 | KMT2A (0.56) | KMT2AMDM2TLR2 | |
| SCHEMBL25357589 | 0.79 | MDM2 (0.56) | KMT2AMDM2TLR2 | |
| SCHEMBL25357584 | 0.79 | MDM2 (0.56) | KMT2AMDM2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352086-A1 | COMPOSITIONS AND METHODS COMPRISING LIPID ASSOCIATED TRANSMEMBRANE DOMAINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-10-24 | — | — | US | disclosed |
| WO-2023028497-A1 | COMPOSITIONS AND METHODS COMPRISING LIPID ASSOCIATED TRANSMEMBRANE DOMAINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240352086-A1 | COMPOSITIONS AND METHODS COMPRISING LIPID ASSOCIATED TRANSMEMBRANE DOMAINS | SDCBP, HDLBP, VAPA | ALB 1200/4885NAALAD2 2085/4885FTO 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.