SCHEMBL1738761

SCHEMBL1738761

CC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
MDM2 Q00987 6/20 0.55
TLR2 O60603 3/20 0.54
MDM4 O15151 1/20 0.52
TP53 P04637 1/20 0.52
CASP3 P42574 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31437099 1.00 KMT2A (0.56) KMT2AMDM2TLR2MDM4TP53
SCHEMBL29401421 1.00 KMT2A (0.56) KMT2AMDM2TLR2MDM4TP53
SCHEMBL31437131 1.00 KMT2A (0.56) KMT2AMDM2TLR2MDM4TP53
SCHEMBL3728827 1.00 KMT2A (0.56) KMT2AMDM2TLR2MDM4TP53
SCHEMBL25357584 0.97 MDM2 (0.56) KMT2AMDM2TLR2MDM4TP53
SCHEMBL25357589 0.97 MDM2 (0.56) KMT2AMDM2TLR2MDM4TP53
SCHEMBL5495444 0.92 FOLH1 (0.57) KMT2AMDM2
SCHEMBL260631 0.92 KMT2A (0.66) KMT2AMDM2TLR2MDM4TP53
SCHEMBL178698 0.92 KMT2A (0.66) KMT2AMDM2TLR2MDM4TP53
SCHEMBL178733 0.92 KMT2A (0.66) KMT2AMDM2TLR2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622991-A2 SYNTHESIS OF A CYCLIC PEPTIDE Janssen Pharmaceutica NV (BE) 2025-10-01 EP claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
CN-115819511-A Preparation method and application of giant salamander hydrolyzed collagen active peptide 广州远想医学生物技术有限公司 2023-03-21 CN claimed
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-04-30 US disclosed
US-20260116922-A1 HIGHLY STABLE OXYTOCIN DERIVATIVES UNIVERSITAET WIEN (AT) 2026-04-30 US disclosed
EP-4729529-A1 PREPARATION OF PEPTIDE INHIBITOR OF INTERLEUKIN-23 RECEPTOR AND USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2026-04-22 EP disclosed
EP-3319984-B1 TAU-BINDING ANTIBODIES UCB Biopharma SRL (BE) 2026-03-11 EP disclosed
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases PROTAGONIST THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 JANSSEN PHARMACEUTICA NV (BE) 2026-01-22 US disclosed
EP-4676595-A1 INTERLEUKIN-23 RECEPTOR ANTAGONIST PEPTIDES FOR USE IN THE TREATMENT OF PSORIASIS Janssen Pharmaceutica NV (BE) 2026-01-14 EP disclosed
US-20260000659-A1 LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR JANSSEN BIOTECH INC (US) 2026-01-01 US disclosed
US-8338565-B2 Macrocyclic compounds for inhibition of tumor necrosis factor alpha ENSEMBLE THERAPEUTICS CORPORATION (US) 2012-12-25 US disclosed
US-8293870-B2 Mucin hypersecretion inhibitors and methods of use BIOMARCK PHARMACEUTICALS LTD (US) 2012-10-23 US disclosed
EP-2399599-A2 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE Biomarck Pharmaceuticals, Ltd. (US) 2011-12-28 EP disclosed
US-20100197607-A1 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE WILLIAMS, MASON L. 2010-08-05 US disclosed
US-20100152099-A1 MACROCYCLIC COMPOUNDS FOR INHIBITION OF TUMOR NECROSIS FACTOR ALPHA ENSEMBLE THERAPEUTICS CORPORATION 2010-06-17 US disclosed
US-20090275520-A1 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE WILLIAMS, MASON L. 2009-11-05 US disclosed
US-7524926-B2 Mucin hypersecretion inhibitors and methods of use BIOMARCK PHARMACEUTICALS, LTD. (US) 2009-04-28 US disclosed
CN-101146545-A Mucin hypersecretion inhibitors based on the structure of MANS and methods of use BIOMARCK PHARMACEUTICALS LTD (US) 2008-03-19 CN disclosed
US-20060205664-A1 Mucin hypersecretion inhibitors and methods of use WILLIAMS, MASON L. 2006-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 IL23R, IL17A, IL36G KMT2A 958/4885MDM2 4433/4885TLR2 1423/4885
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL17A, IL36G KMT2A 1851/4885MDM2 3462/4885TLR2 133/4885
US-20260000659-A1 LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR IL23R, IL36G, IL15RA KMT2A 3239/4885MDM2 3323/4885TLR2 173/4885
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, IL36G KMT2A 4698/4885MDM2 3296/4885TLR2 1030/4885
US-20100152099-A1 MACROCYCLIC COMPOUNDS FOR INHIBITION OF TUMOR NECROSIS FACTOR ALPHA TNF, CD40, TNFRSF1A KMT2A 4176/4885MDM2 1236/4885TLR2 883/4885
US-20260116922-A1 HIGHLY STABLE OXYTOCIN DERIVATIVES OXTR, CRH, TRHR KMT2A 3331/4885MDM2 3967/4885TLR2 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.