Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237763 | 1.00 | NR1H2 (0.35) | NR1H2NR1H3DGAT1CDK8HRH1 | |
| SCHEMBL29237738 | 0.90 | NR1H2 (0.30) | NR1H2NR1H3 | |
| SCHEMBL29237626 | 0.90 | NR1H2 (0.30) | NR1H2NR1H3DGAT1HRH1HRH4 | |
| SCHEMBL30217011 | 0.90 | NR1H2 (0.30) | NR1H2NR1H3 | |
| SCHEMBL30217171 | 0.90 | NR1H2 (0.30) | NR1H2NR1H3DGAT1HRH1HRH4 | |
| SCHEMBL30217259 | 0.87 | BRAF (0.33) | DGAT1 | |
| SCHEMBL29237524 | 0.87 | ALDH1A1 (0.33) | DGAT1CDK8 | |
| SCHEMBL30217061 | 0.87 | ALDH1A1 (0.33) | DGAT1CDK8 | |
| SCHEMBL30967813 | 0.86 | NR1H2 (0.30) | NR1H2NR1H3DGAT1 | |
| SCHEMBL30285398 | 0.85 | SMN1; SMN2 (0.34) | NR1H2NR1H3DGAT1HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |