SCHEMBL30217551

SCHEMBL30217551

Clc1ccc(C2C=CC(Br)=CC2)cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HTR3A P46098 1/20 0.31
PRCP P42785 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30217469 1.00 SLC6A2 (0.32) SLC6A2SLC6A3HTR3APRCPHTR2A
SCHEMBL14313656 0.85 KDM1A (0.36) HTR2CHTR2B
SCHEMBL148194 0.68 LMNA (0.44) SLC6A2SLC6A3HTR3AHTR2AHTR2C
SCHEMBL28949260 0.67 SLC6A2 (0.38) SLC6A2SLC6A3HTR3AHTR2AHTR2C
SCHEMBL30217447 0.67 SLC6A2 (0.38) SLC6A2SLC6A3HTR3AHTR2AHTR2C
SCHEMBL30317873 0.64 NOS3 (0.39) SLC6A2SLC6A3PRCPHTR2AHTR2C
SCHEMBL14708313 0.64
SCHEMBL13442908 0.62
SCHEMBL17189604 0.60
SCHEMBL12811254 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667250-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2023-01-31 CN disclosed