Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26076423 | 0.85 | MAPT (0.34) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL22031805 | 0.85 | MAPT (0.34) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL13873152 | 0.84 | KMT2A (0.44) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL3014458 | 0.80 | AKR1B1 (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL18191124 | 0.80 | ALDH1A1 (0.35) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL7638197 | 0.79 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL3021784 | 0.78 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL3021788 | 0.78 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL3785204 | 0.78 | ABCB1 (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL509000 | 0.77 | ABCB1 (0.39) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379509-B1 | HERBICIDAL AND INSECTICIDAL PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER IP GMBH (DE) | 2016-02-17 | — | — | EP | disclosed |
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | KMT2A 1579/4885SMN1; SMN2 3492/4885MEN1 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.