⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213505 | 0.79 | — | — | |
| SCHEMBL10392314 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL447993 | 0.75 | — | — | |
| SCHEMBL7995031 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL2840987 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL38852 | 0.69 | — | — | |
| SCHEMBL8076785 | 0.69 | — | — | |
| SCHEMBL19817574 | 0.67 | — | — | |
| SCHEMBL72618 | 0.67 | — | — | |
| SCHEMBL107778 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106892855-A | New compound, color dispersion liquid, colored curable resin composition, colour filter and display device | 东友精细化工有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-103524392-A | Azetidines as mek inhibitors for the treatment of proliferative diseases | EXELIXIS INC | 2014-01-22 | — | — | CN | disclosed |
| CN-101365676-B | Azetidines as mek inhibitors for the treatment of proliferative diseases | EXELIXIS INC | 2013-09-11 | — | — | CN | disclosed |
| CN-1810802-B | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP | 2011-04-27 | — | — | CN | disclosed |
| CN-1726209-B | 3-substituted-4-pyrimidone derivatives | SANOFI AVENTIS | 2011-04-13 | — | — | CN | disclosed |
| EP-1745002-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-11-03 | — | — | EP | disclosed |
| US-20100210653-A1 | Novel Compounds, Their Preparations and Use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-08-19 | — | — | US | disclosed |
| CN-1764650-B | 2, 3, 6-trisubstituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP | 2010-06-16 | — | — | CN | disclosed |
| CN-100488958-C | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP SANOFI (JP) | 2009-05-20 | — | — | CN | disclosed |
| CN-101365676-A | Azetidines as mek inhibitors for the treatment of proliferative diseases | EXELIXIS INC (US) | 2009-02-11 | — | — | CN | disclosed |
| EP-1745002-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2007-01-24 | — | — | EP | disclosed |
| CN-1810802-A | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP (JP) | 2006-08-02 | — | — | CN | disclosed |
| CN-1764650-A | 2, 3, 6-trisubstituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1726209-A | 3-substituted-4-pyrimidone derivatives | SANOFI AVENTIS (JP) | 2006-01-25 | — | — | CN | disclosed |
| WO-2005105725-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2005-11-10 | — | — | WO | disclosed |
| CN-1556804-A | 3-substituted-4-pyrimidone derivatives | ������ҩ��ʽ���� | 2004-12-22 | — | — | CN | disclosed |
| CN-1555367-A | 3-substituted-4-pyrimidone derivatives | ������ҩ��ʽ���� | 2004-12-15 | — | — | CN | disclosed |
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |