Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394860 | 1.00 | TRPA1 (0.32) | TRPA1NOTUMMAPT | |
| SCHEMBL379612 | 0.77 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL379614 | 0.77 | TRPA1 (0.33) | TRPA1 | |
| Fluoride SCHEMBL28557472 | 0.75 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL30816755 | 0.71 | MEN1 (0.33) | TRPA1MAPT | |
| SCHEMBL692060 | 0.70 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL1954384 | 0.70 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL323897 | 0.70 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL9958734 | 0.70 | GRK6 (0.34) | — | |
| SCHEMBL2186647 | 0.69 | KDM4E (0.33) | TRPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023033742-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-03-09 | — | — | WO | disclosed |