Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30218353 | 0.76 | SMN1; SMN2 (0.38) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7486679 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2WDR5CYP2C19 | |
| SCHEMBL9760582 | 0.75 | KDM4E (0.61) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28428637 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2WDR5CYP2C19 | |
| SCHEMBL9588769 | 0.74 | ALDH1A1 (0.72) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15154544 | 0.73 | AHR (0.56) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4220932 | 0.72 | HTT (0.46) | ALDH1A1KDM4ESMN1; SMN2KMT2AWDR5 | |
| SCHEMBL15154191 | 0.72 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5048604 | 0.71 | HTT (0.45) | ALDH1A1KDM4ESMN1; SMN2KMT2AWDR5 | |
| SCHEMBL6478378 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867532-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |