Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588769 | 0.82 | ALDH1A1 (0.72) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6173251 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6578990 | 0.76 | ALDH1A1 (0.64) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30218346 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9256830 | 0.74 | ALDH1A1 (0.61) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29368738 | 0.73 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6907648 | 0.73 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15154427 | 0.72 | SRC (0.60) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11780453 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29206051 | 0.71 | KCNA3 (0.56) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049381-A | Skin coloring compositions containing indoles and quaternary ammonium salts | CLAIROL INCORPORATED (US) | 1991-09-17 | — | — | US | disclosed |