Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.47 |
| ▸ | FEN1 | P39748 | 5/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119904 | 1.00 | ALOX5AP (0.47) | ALOX5APFEN1HPGDSACKR3PRMT5 | |
| SCHEMBL29119906 | 1.00 | ALOX5AP (0.47) | ALOX5APFEN1HPGDSACKR3PRMT5 | |
| SCHEMBL30218114 | 1.00 | ALOX5AP (0.47) | ALOX5APFEN1HPGDSACKR3PRMT5 | |
| SCHEMBL29179670 | 0.92 | ALOX5AP (0.40) | ALOX5APFEN1HPGDSACKR3PRMT5 | |
| SCHEMBL29179669 | 0.92 | ALOX5AP (0.40) | ALOX5APFEN1HPGDSACKR3PRMT5 | |
| SCHEMBL1098537 | 0.83 | ALOX5AP (0.36) | ALOX5APFEN1MEN1KMT2AGPR119 | |
| SCHEMBL28037357 | 0.82 | FEN1 (0.51) | ALOX5APFEN1HPGDSACKR3BACE1 | |
| SCHEMBL30088909 | 0.80 | GPR119 (0.51) | ALOX5APFEN1HPGDSPRMT5USP30 | |
| SCHEMBL27177267 | 0.80 | GPR119 (0.51) | ALOX5APFEN1HPGDSPRMT5USP30 | |
| SCHEMBL28347844 | 0.80 | USP30 (0.46) | ALOX5APFEN1USP30MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751117-A | SARM1 enzyme activity inhibitor and application thereof | 科辉智药生物科技（无锡）有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-115724839-A | SARM1 enzyme activity inhibitor and application thereof | 科辉智药生物科技(深圳)有限公司 | 2023-03-03 | — | — | CN | disclosed |