Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 6/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15034627 | 0.93 | FEN1 (0.51) | FEN1ALOX5APBACE1ACKR3CTSD | |
| SCHEMBL28037370 | 0.88 | ALOX5AP (0.47) | FEN1ALOX5APBACE1 | |
| SCHEMBL28265325 | 0.85 | NR1D1 (0.42) | FEN1ALOX5APBACE1ACKR3CTSD | |
| SCHEMBL29119904 | 0.82 | ALOX5AP (0.47) | FEN1ALOX5APBACE1ACKR3CTSD | |
| SCHEMBL30218474 | 0.82 | ALOX5AP (0.47) | FEN1ALOX5APBACE1ACKR3CTSD | |
| SCHEMBL30218114 | 0.82 | ALOX5AP (0.47) | FEN1ALOX5APBACE1ACKR3CTSD | |
| SCHEMBL29119906 | 0.82 | ALOX5AP (0.47) | FEN1ALOX5APBACE1ACKR3CTSD | |
| SCHEMBL22544369 | 0.81 | PKM (0.38) | FEN1ALOX5APFNTAFNTB | |
| SCHEMBL28266724 | 0.79 | MTOR (0.38) | FEN1ALOX5AP | |
| SCHEMBL22544386 | 0.77 | PIK3CA (0.38) | FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-B | Pyridine pyrimidinamine compound or pyridine pyridyl amine compound and its application | 广州必贝特医药技术有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |