SCHEMBL30218698

SCHEMBL30218698

Cc1cc(C(=O)O)c(C)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MYC P01106 3/20 0.44
ALOX15 P16050 1/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
CYP2C9 P11712 2/20 0.44
THRB P10828 2/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
ATIC P31939 1/20 0.44
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
PRNP P04156 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
KDM4E B2RXH2 3/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
AKR1B10 O60218 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18936275 1.00 ALDH1A1 (0.47) ALDH1A1MYCALOX15HPGDHSD17B10
SCHEMBL10551727 0.84 MAPT (0.47) ALDH1A1HPGDHSD17B10RXFP1KDM4E
SCHEMBL5337894 0.82 ALDH1A1 (0.50) ALDH1A1MYCALOX15HPGDHSD17B10
SCHEMBL7596065 0.82 THRB (0.67) ALDH1A1MYCALOX15HPGDHSD17B10
SCHEMBL10343413 0.82 HSD17B10 (0.67) ALDH1A1HPGDHSD17B10CYP2C9THRB
SCHEMBL28650743 0.79 ALDH1A1 (0.46) ALDH1A1MYCHPGDHSD17B10CYP2C9
SCHEMBL5235427 0.79 ALDH1A1 (0.48) ALDH1A1MYCALOX15HPGDHSD17B10
SCHEMBL18936303 0.78 KDM4E (0.50) ALDH1A1MYCHPGDHSD17B10CYP2C9
SCHEMBL30218700 0.78 KDM4E (0.50) ALDH1A1MYCHPGDHSD17B10CYP2C9
SCHEMBL27966955 0.75 HTT (0.58) ALDH1A1HPGDHSD17B10CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699003-B Catalytic hydrogenation process for preparing pyrazoles 巴斯夫欧洲公司 2023-02-03 CN disclosed