SCHEMBL30219465

SCHEMBL30219465

ON=C(c1ccc(OCCOc2ccccc2)cc1)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.53
PARP10 Q53GL7 1/20 0.50
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 2/20 0.46
GAA P10253 2/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HDAC1 Q13547 5/20 0.45
HDAC2 Q92769 5/20 0.45
RECQL P46063 1/20 0.43
KCNA3 P22001 1/20 0.42
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4665179 0.88 GAA (0.50) MAPTRAB9AALDH1A1GAAALOX15
SCHEMBL4665182 0.88 GAA (0.50) MAPTRAB9AALDH1A1GAAALOX15
SCHEMBL7249593 0.85 GAA (0.50) PARP10ALDH1A1GAAALOX15HSD17B10
SCHEMBL7249591 0.85 GAA (0.50) PARP10ALDH1A1GAAALOX15HSD17B10
SCHEMBL30219433 0.84 NR4A2 (0.55) PARP10MAPTRAB9AGAAHDAC6
SCHEMBL27174661 0.81 NPC1 (0.50) PKMMAPTRAB9AALDH1A1GAA
SCHEMBL27174664 0.81 NPC1 (0.50) PKMMAPTRAB9AALDH1A1GAA
SCHEMBL7244525 0.80 TP53 (0.62) MAPTRAB9AGAAALOX15HSD17B10
SCHEMBL7244527 0.80 TP53 (0.62) MAPTRAB9AGAAALOX15HSD17B10
SCHEMBL7246417 0.80 TP53 (0.62) MAPTRAB9AGAAALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11884839-B2 Acetal-protected silanol group-containing polysiloxane composition NISSAN CHEMICAL CORPORATION (JP) 2024-01-30 US disclosed
US-20230125270-A1 RADIATION SENSITIVE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-04-27 US disclosed
US-11561472-B2 Radiation sensitive composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11561472-B2 Radiation sensitive composition RER1, RAD1, RAD51 PKM 1701/4885PARP10 1693/4885MAPT 3291/4885
US-20230125270-A1 RADIATION SENSITIVE COMPOSITION XRCC6, RAD50, XRCC5 PKM 2346/4885PARP10 773/4885MAPT 3609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.