Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24896464 | 0.85 | KDM4E (0.39) | HCRTR1HCRTR2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30220538 | 0.82 | DHODH (0.40) | MAOAJMJD6ALDH1A1LMNAPIK3CA | |
| SCHEMBL30220598 | 0.80 | DGAT1 (0.40) | HCRTR1HCRTR2ENPP2ALDH1A1PIK3CA | |
| SCHEMBL30220535 | 0.79 | JMJD6 (0.41) | JMJD6ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL30220530 | 0.77 | SMN1; SMN2 (0.41) | JMJD6ALDH1A1PIK3CAMAPTKDM4E | |
| SCHEMBL30220571 | 0.77 | CDC7 (0.41) | JMJD6ALDH1A1PIK3CAMAPTHPGD | |
| SCHEMBL25003510 | 0.77 | ACACB (0.35) | ACACB | |
| SCHEMBL30220568 | 0.76 | KDM4E (0.45) | JMJD6ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL24896382 | 0.76 | GRM4 (0.35) | ACACB | |
| SCHEMBL24896463 | 0.74 | LRRK2 (0.38) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370207-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023287704-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2023-01-19 | — | — | WO | disclosed |