Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24896464 | 0.78 | KDM4E (0.39) | HCRTR1HCRTR2GRM4 | |
| SCHEMBL24896309 | 0.77 | CCNA2 (0.33) | — | |
| SCHEMBL30220512 | 0.74 | MAOA (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL24896380 | 0.74 | DYRK1A (0.36) | — | |
| SCHEMBL29942068 | 0.74 | RXFP1 (0.37) | — | |
| SCHEMBL23755342 | 0.74 | RXFP1 (0.37) | — | |
| SCHEMBL24896382 | 0.69 | GRM4 (0.35) | GRM4 | |
| SCHEMBL25003510 | 0.68 | ACACB (0.35) | GRM4 | |
| SCHEMBL24896465 | 0.65 | KMO (0.35) | LRRK2GRM4 | |
| SCHEMBL29721829 | 0.63 | TRIM24 (0.46) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287704-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2023-01-19 | — | — | WO | disclosed |