Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802747 | 1.00 | NOTUM (0.47) | NOTUMMEN1KMT2AATMHPGD | |
| SCHEMBL23856155 | 0.87 | NOTUM (0.51) | NOTUMMEN1KMT2AATMHPGD | |
| SCHEMBL30062687 | 0.87 | NOTUM (0.51) | NOTUMMEN1KMT2AATMHPGD | |
| SCHEMBL18379695 | 0.79 | ESR2 (0.48) | MEN1KMT2AMAPT | |
| SCHEMBL30585082 | 0.79 | ESR2 (0.48) | MEN1KMT2AMAPT | |
| SCHEMBL22363438 | 0.77 | NOTUM (0.44) | NOTUMHSP90AA1HSP90AB1ALDH1A1ENPP2 | |
| SCHEMBL21936088 | 0.76 | CHRNB2 (0.38) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL23856146 | 0.76 | HPGD (0.47) | HPGDHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL27940431 | 0.76 | HPGD (0.47) | HPGDHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL30836656 | 0.75 | ADRA1A (0.40) | MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126858-B1 | DIHYDRO-2-PYRROLO[3,4-C]PYRIDINE DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS | RICHTER GEDEON NYRT (HU) | 2026-03-18 | — | — | EP | disclosed |
| CN-115279747-B | FYN and VEGFR2 kinase inhibitors | 罗达制药生物技术有限责任公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-112955446-B | 6-Fluoro-2-methylbenzo [ D ] thiazol-5-yl compounds | 伊莱利利公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-4126858-A1 | DIHYDRO-2-PYRROLO[3,4-C]PYRIDINE DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS | Richter Gedeon Nyrt. (HU) | 2023-02-08 | — | — | EP | disclosed |