SCHEMBL30222010

SCHEMBL30222010

CC(C)(C)P(c1ccc2ccccc2c1-c1c(P(C(C)(C)C)C(C)(C)C)ccc2ccccc12)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
CYP2A6 P11509 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TSHR P16473 3/20 0.42
HSD17B10 Q99714 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPRT1 P00492 1/20 0.39
CYP1A2 P05177 1/20 0.38
WDR5 P61964 1/20 0.37
HIF1A Q16665 2/20 0.37
CYP1B1 Q16678 1/20 0.37
DNMT1 P26358 1/20 0.36
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
RAB9A P51151 1/20 0.34
CASP7 P55210 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2023656 1.00 MAPT (0.42) MAPTCYP2A6ALDH1A1TSHRHSD17B10
SCHEMBL202312 0.88 DHFR (0.40) MAPTCYP2A6ALDH1A1TSHRHSD17B10
SCHEMBL29376410 0.88 DHFR (0.40) MAPTCYP2A6ALDH1A1TSHRHSD17B10
SCHEMBL3656667 0.88 DHFR (0.40) MAPTCYP2A6ALDH1A1TSHRHSD17B10
SCHEMBL227099 0.87 MAPT (0.34) MAPTCYP2A6ALDH1A1TSHRHSD17B10
SCHEMBL2017985 0.87 MAPT (0.67) MAPTALDH1A1HPGDRAB9ANQO2
SCHEMBL30170935 0.87 MAPT (0.34) MAPTCYP2A6ALDH1A1TSHRHSD17B10
SCHEMBL29511657 0.87 MAPT (0.67) MAPTALDH1A1HPGDRAB9ANQO2
SCHEMBL28450466 0.84 MAPT (0.33) MAPTCYP2A6ALDH1A1TSHRHSD17B10
SCHEMBL29583072 0.83 MAPT (0.47) MAPTTDP1CYP1A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027048-A Nitrogen-containing heteropolycyclic compound, material, element, display device, and lighting device 爱思开新材料捷恩智株式会社 2024-05-14 CN disclosed
CN-115894533-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-04-04 CN disclosed
CN-115873003-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2023-03-31 CN disclosed