Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227099 | 1.00 | MAPT (0.34) | MAPTCHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL30222010 | 0.87 | MAPT (0.42) | MAPTALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL2023656 | 0.87 | MAPT (0.42) | MAPTALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL6519885 | 0.80 | MAPT (0.39) | MAPTCHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL4425865 | 0.79 | MAPT (0.34) | MAPTCHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL24272784 | 0.77 | NR1I2 (0.32) | MCL1SIGMAR1GAACYP2D6 | |
| SCHEMBL3656667 | 0.76 | DHFR (0.40) | MAPTALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL202312 | 0.76 | DHFR (0.40) | MAPTALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL29376410 | 0.76 | DHFR (0.40) | MAPTALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL2017985 | 0.76 | MAPT (0.67) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105384-B | Preparation method of carbazole and fluorene organic electroluminescent intermediate | 江苏广域化学有限公司 | 2022-11-01 | — | — | CN | disclosed |