Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022350 | 1.00 | FAAH (0.50) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL3022284 | 1.00 | FAAH (0.50) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL4651883 | 0.93 | ATM (0.53) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL4651891 | 0.93 | ATM (0.53) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL4653011 | 0.93 | ATM (0.53) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL4651888 | 0.93 | ATM (0.53) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL4653014 | 0.93 | ATM (0.53) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL7988140 | 0.88 | TSHR (0.54) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL30115067 | 0.88 | HCAR2 (0.63) | FAAHMAPTTERTPTPN1PPARG | |
| SCHEMBL489595 | 0.87 | MAPT (0.66) | FAAHMAPTTERTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457567-B1 | Agent having neurotrophic factor-like activity | NAGOYA IND SCIENCE RES INST (JP) | 2015-12-30 | — | — | EP | disclosed |
| EP-2695613-A1 | ANALGESIC | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2014-02-12 | — | — | EP | disclosed |
| EP-2695613-A1 | ANALGESIC | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2014-02-12 | — | — | EP | disclosed |
| EP-2671578-A1 | PROPHYLACTIC OR THERAPEUTIC DRUG FOR PERIPHERAL NEUROPATHY CAUSED BY ANTICANCER AGENT | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2013-12-11 | — | — | EP | disclosed |
| US-20130296426-A1 | ANALGESIC | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296426-A1 | ANALGESIC | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296425-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR A PERIPHERAL NERVE DISORDER INDUCED BY ANTI-CANCER AGENTS | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296425-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR A PERIPHERAL NERVE DISORDER INDUCED BY ANTI-CANCER AGENTS | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296425-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR A PERIPHERAL NERVE DISORDER INDUCED BY ANTI-CANCER AGENTS | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296426-A1 | ANALGESIC | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2013-11-07 | — | — | US | disclosed |
| EP-2457567-A1 | Agent having neurotrophic factor-like activity | Nagoya Industrial Science Research Institute (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-20100204498-A1 | AGENT HAVING NEUROTROPHIC FACTOR-LIKE ACTIVITY | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2010-08-12 | — | — | US | disclosed |
| EP-2204172-A1 | AGENT HAVING NEUROTROPHIC FACTOR-LIKE ACTIVITY | Nagoya Industrial Science Research Institute (JP) | 2010-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296425-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR A PERIPHERAL NERVE DISORDER INDUCED BY ANTI-CANCER AGENTS | ALOX5, CPT1B, PMP22 | FAAH 26/4885MAPT 4360/4885TERT 2761/4885 |
| US-20130296426-A1 | ANALGESIC | CNTN1, SHARPIN, HCAR2 | FAAH 36/4885MAPT 2871/4885TERT 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.