Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30224216 | 0.82 | — | — | |
| SCHEMBL30224944 | 0.81 | LIPE (0.33) | CHRNA7 | |
| SCHEMBL23994458 | 0.81 | CHRNB2 (0.47) | CHRNA7 | |
| SCHEMBL30181803 | 0.81 | CHRNB2 (0.47) | CHRNA7 | |
| SCHEMBL25004997 | 0.81 | CHRNB2 (0.47) | CHRNA7 | |
| SCHEMBL23994030 | 0.79 | HTR2C (0.45) | KDM1AMAOBMAOACHRNA7 | |
| SCHEMBL23994065 | 0.79 | HTR2C (0.45) | KDM1AMAOBMAOACHRNA7 | |
| SCHEMBL23994772 | 0.79 | HTR2C (0.45) | KDM1AMAOBMAOACHRNA7 | |
| SCHEMBL25004725 | 0.79 | HTR2C (0.45) | KDM1AMAOBMAOACHRNA7 | |
| SCHEMBL30181920 | 0.76 | KDM1A (0.33) | KDM1AMAOACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143194-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |