Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992898 | 1.00 | BACE1 (0.38) | BACE1ALDH1A1KMT2APKMSMN1; SMN2 | |
| SCHEMBL17275707 | 0.82 | ALDH1A1 (0.47) | BACE1ALDH1A1KMT2APKMSMN1; SMN2 | |
| SCHEMBL23993885 | 0.82 | BACE1 (0.39) | BACE1PKMANPEP | |
| SCHEMBL23992901 | 0.81 | RXRA (0.34) | MAPTSTING1LMNATP53TDP1 | |
| SCHEMBL23994439 | 0.79 | TP53 (0.48) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL23993590 | 0.78 | RXRA (0.35) | BACE1KMT2AMEN1STING1LMNA | |
| SCHEMBL22479422 | 0.77 | BACE1 (0.36) | BACE1PKMANPEP | |
| SCHEMBL31729612 | 0.77 | BACE1 (0.36) | BACE1PKMANPEP | |
| SCHEMBL13341336 | 0.77 | BACE1 (0.32) | BACE1TDP1 | |
| SCHEMBL2824816 | 0.76 | MAPT (0.44) | ALDH1A1KMT2APKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090514-A1 | COVALENT SARM1 INHIBITORS | NURA BIO, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| EP-4143194-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |