SCHEMBL30224951

SCHEMBL30224951

NC(=O)c1cc(=O)c2ccc(F)cc2o1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.53
AKR1B1 P15121 3/20 0.51
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
MCHR1 Q99705 7/20 0.49
KCNH2 Q12809 4/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 1/20 0.47
USP2 O75604 1/20 0.46
CSNK2A2 P19784 1/20 0.46
PTGS1 P23219 1/20 0.46
CSNK2B P67870 1/20 0.46
CSNK2A1 P68400 1/20 0.46
CSNK2A3 Q8NEV1 1/20 0.46
NQO1 P15559 1/20 0.45
MCHR2 Q969V1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9752059 0.87 GABRP (0.55) MAOBMCHR1KCNH2KMT2AKDM4E
SCHEMBL5564116 0.87 AKR1B1 (0.69) MAOBAKR1B1CYP11B1CYP11B2MCHR1
SCHEMBL29495395 0.87 AKR1B1 (0.69) MAOBAKR1B1CYP11B1CYP11B2MCHR1
Hydrochloric Acid SCHEMBL30224994 0.85 GABRP (0.54) MAOBMCHR1KCNH2KMT2AKDM4E
SCHEMBL5188789 0.81 AKR1B1 (0.76) MAOBAKR1B1KMT2AKDM4EALDH1A1
SCHEMBL30225130 0.81 AKR1B1 (0.76) MAOBAKR1B1KMT2AKDM4EALDH1A1
SCHEMBL8106900 0.80 POLB (0.62) AKR1B1KMT2AKDM4EALDH1A1
SCHEMBL6332284 0.78 AKR1B1 (0.74) MAOBAKR1B1CYP11B1CYP11B2MCHR1
SCHEMBL8116101 0.78 AKR1B1 (0.55) MAOBAKR1B1MCHR1KCNH2KMT2A
SCHEMBL29569747 0.77 KDM4E (0.74) MAOBKMT2AKDM4EALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641864-B Anti-infective agents 邓迪大学 2023-04-04 CN disclosed