SCHEMBL5564116

SCHEMBL5564116

O=C(O)c1cc(=O)c2ccc(F)cc2o1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.69
KDM4E B2RXH2 3/20 0.63
USP2 O75604 1/20 0.63
CSNK2A2 P19784 1/20 0.63
PTGS1 P23219 1/20 0.63
CSNK2B P67870 1/20 0.63
CSNK2A1 P68400 1/20 0.63
CSNK2A3 Q8NEV1 1/20 0.63
ALDH1A1 P00352 2/20 0.61
MAOB P27338 3/20 0.56
MCHR1 Q99705 4/20 0.50
KCNH2 Q12809 2/20 0.50
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
KMT2A Q03164 2/20 0.47
POLB P06746 2/20 0.46
LMNA P02545 1/20 0.46
NQO1 P15559 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495395 1.00 AKR1B1 (0.69) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL2318176 0.87 ALDH1A1 (0.67) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL30224951 0.87 MAOB (0.53) AKR1B1KDM4EUSP2CSNK2A2PTGS1
Hydrochloric Acid SCHEMBL8858723 0.85 ALDH1A1 (0.65) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL4248840 0.81 AKR1B1 (0.71) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL5275063 0.81 AKR1B1 (1.00) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL18397901 0.80 AKR1B1 (0.69) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL10649648 0.80 AKR1B1 (0.69) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL6331139 0.80 ALDH1A1 (0.77) AKR1B1KDM4EUSP2CSNK2A2PTGS1
SCHEMBL5084426 0.80 AKR1B1 (0.69) AKR1B1KDM4EUSP2CSNK2A2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260128372-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEMICAL LTD (KR) 2026-05-07 US disclosed
EP-4576305-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEM, LTD. (KR) 2025-06-25 EP disclosed
CN-120153509-A Nonaqueous electrolyte for lithium secondary battery and lithium secondary battery comprising same 株式会社LG化学 2025-06-13 CN disclosed
CN-118666733-A Application of tetrahydrocarbazole micromolecule compounds in preparation of antiviral drugs and preparation method thereof 中国人民解放军空军军医大学 2024-09-20 CN disclosed
WO-2024107030-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME 주식회사 엘지화학 2024-05-23 WO disclosed
US-20240018133-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ABBVIE INC. 2024-01-18 US disclosed
CN-109641864-B Anti-infective agents 邓迪大学 2023-04-04 CN disclosed
US-11485720-B2 Anti-infective agents UNIVERSITY OF DUNDEE (GB) 2022-11-01 US disclosed
EP-3472141-B1 ANTI-INFECTIVE AGENTS UNIV DUNDEE (GB) 2022-10-05 EP disclosed
CN-114401952-A Substituted cycloalkyl compounds as modulators of integrated stress pathways 卡里科生命科学有限责任公司 2022-04-26 CN disclosed
EP-1606278-A1 SUBSTITUTED CYCLOHEXYL AND PIPERIDINYL DERIVATES AS MELANOCORTIN-4 RECEPTOR MODULATORS Santhera Pharmaceuticals (Schweiz) GmbH (CH) 2005-12-21 EP disclosed
EP-1603911-A1 SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS Santhera Pharmaceuticals (Schweiz) GmbH (CH) 2005-12-14 EP disclosed
EP-1603912-A1 SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS Santhera Pharmaceuticals (Schweiz) GmbH (CH) 2005-12-14 EP disclosed
US-20050209274-A1 Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor ABOTT LABORATORIES 2005-09-22 US disclosed
WO-2004083199-A1 SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) 2004-09-30 WO disclosed
WO-2004083208-A1 SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) 2004-09-30 WO disclosed
WO-2004083209-A1 SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) 2004-09-30 WO disclosed
WO-2004083198-A1 SUBSTITUTED CYCLOHEXYL AND PIPERIDINYL DERIVATES AS MELANOCORTIN-4 RECEPTOR MODULATORS SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) 2004-09-30 WO disclosed
US-6552054-B1 For prophylaxis and therapy of bone diseases and chondropathy TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-04-22 US disclosed
EP-1211251-A1 CHROMONE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF Takeda Chemical Industries, Ltd. (JP) 2002-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485720-B2 Anti-infective agents C1R, RRS1, ARG1 AKR1B1 2303/4885KDM4E 2159/4885USP2 3354/4885
US-20240018133-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 AKR1B1 1312/4885KDM4E 4640/4885USP2 1932/4885
US-20260128372-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME CLCN2, CLIC1, RER1 AKR1B1 604/4885KDM4E 3702/4885USP2 4637/4885
US-20050209274-A1 Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor MCHR1, MCHR2, MC1R AKR1B1 1927/4885KDM4E 2305/4885USP2 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.