Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832547 | 0.78 | LMNA (0.48) | LMNAMAPTPOLBMEN1CYP1A2 | |
| SCHEMBL25433262 | 0.68 | SRD5A1 (0.40) | — | |
| SCHEMBL5657114 | 0.66 | OPRM1 (0.45) | DAOHPGDCHRM2CHRM4CHRM1 | |
| SCHEMBL104742 | 0.65 | LMNA (0.63) | LMNAMAPTPOLBMEN1CYP1A2 | |
| SCHEMBL8556280 | 0.65 | PIK3CD (0.35) | MAPTKMT2AHPGDCHRM2CHRM4 | |
| SCHEMBL2718551 | 0.64 | LMNA (0.51) | LMNAMAPTPOLBMEN1CYP1A2 | |
| SCHEMBL16455979 | 0.64 | CHRM1 (0.62) | MAPTMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL319049 | 0.63 | CHRM1 (0.70) | CHRM2CHRM4CHRM1CHRM3OPRM1 | |
| Water SCHEMBL28348965 | 0.63 | PIK3CD (0.34) | MAPTKMT2AHPGDCHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL10768662 | 0.63 | PIK3CD (0.34) | MAPTKMT2AHPGDCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4121043-A1 | MDM2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |