Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 12/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29306660 | 0.74 | SPHK1 (0.50) | SPHK1NAAAEPHX1EPHX2 | |
| SCHEMBL4678180 | 0.74 | SPHK1 (0.54) | SPHK1NAAAEPHX1 | |
| SCHEMBL8395995 | 0.72 | SPHK1 (0.55) | SPHK1NAAAEPHX1EPHX2 | |
| SCHEMBL8395145 | 0.72 | SPHK1 (0.55) | SPHK1NAAAEPHX1EPHX2 | |
| SCHEMBL8396618 | 0.72 | SPHK1 (0.55) | SPHK1NAAAEPHX1EPHX2 | |
| SCHEMBL22170867 | 0.72 | PAOX (0.46) | SPHK1 | |
| SCHEMBL29093515 | 0.70 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL29093516 | 0.70 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL16618457 | 0.69 | SPHK1 (0.59) | SPHK1NAAAEPHX1 | |
| SCHEMBL5439484 | 0.69 | SPHK1 (0.44) | SPHK1NAAAEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121043-A1 | MDM2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |