Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 10/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077833 | 0.82 | ACHE (0.34) | ALOX15ACHEBCHEFAAHCHRNB2 | |
| SCHEMBL2777834 | 0.78 | MEN1 (0.45) | ALOX15ACHEBCHE | |
| SCHEMBL13735517 | 0.75 | — | — | |
| SCHEMBL12877872 | 0.74 | TDP1 (0.44) | ACHEBCHEFAAHCHRNB2CHRNA4 | |
| SCHEMBL2778900 | 0.74 | — | — | |
| SCHEMBL11344389 | 0.73 | ACHE (0.33) | ACHEBCHEFAAHCHRNB2CHRNA4 | |
| SCHEMBL2099259 | 0.72 | — | — | |
| SCHEMBL5459979 | 0.71 | — | — | |
| SCHEMBL293056 | 0.71 | — | — | |
| SCHEMBL8888937 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121043-A1 | MDM2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |