SCHEMBL302269

SCHEMBL302269

Cc1c(N)cc2c(c1C)C(c1ccc(N(C)C)cc1)(c1ccc(N(C)C)cc1)OC2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
ALDH1A1 P00352 4/20 0.56
TDP1 Q9NUW8 4/20 0.56
CYP3A4 P08684 3/20 0.56
HSD17B10 Q99714 2/20 0.56
HPGD P15428 1/20 0.56
HIF1A Q16665 1/20 0.56
POLB P06746 2/20 0.38
LMNA P02545 3/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 2/20 0.35
ALOX15 P16050 2/20 0.35
ESR1 P03372 1/20 0.35
TYMS P04818 1/20 0.35
TSHR P16473 1/20 0.35
ESR2 Q92731 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1727670 0.92 MEN1 (0.50) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL10434322 0.90 TDP1 (0.57) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL1728542 0.89 MEN1 (0.47) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL11041419 0.88 MEN1 (0.51) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL10434290 0.84 MEN1 (0.50) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL10434310 0.82 MEN1 (0.48) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL10979156 0.82 KMT2A (0.55) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL8417651 0.80 ALDH1A1 (0.56) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL10434351 0.79 KMT2A (0.47) MEN1KMT2AALDH1A1TDP1CYP3A4
SCHEMBL29723848 0.75 ALDH1A1 (0.57) MEN1KMT2AALDH1A1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2012500865-A 2012-01-12 JP claimed
EP-2328731-A1 ENHANCED SURFACES, COATINGS, AND RELATED METHODS Innova Dynamics, Inc. (US) 2011-06-08 EP claimed
WO-2010022353-A1 ENHANCED SURFACES, COATINGS, AND RELATED METHODS INNOVA METERIALS, LLC (US) 2010-02-25 WO claimed
US-20030207787-A1 Composition capable of indicating by color change when consumer articles, particularly volatile material dispensers, containing or associated with the composition have become inefficient in use. The composition includes:a volatile and FIRMENICH SA (CH) 2003-11-06 US claimed
EP-1342081-A2 COMPOSITIONS ABLE TO INDICATE WHEN THEY BECOME INEFFICIENT IN USE Firmenich S.A. (CH) 2003-09-10 EP claimed
US-20020110498-A1 Compositions able to indicate when they become inefficient in use FIRMENICH SA (CH) 2002-08-15 US claimed
WO-2002046743-A2 COMPOSITIONS ABLE TO INDICATE WHEN THEY BECOME INEFFICIENT IN USE FIRMENICH S.A. (CH) 2002-06-13 WO claimed
US-10105875-B2 Enhanced surfaces, coatings, and related methods CAM HOLDING CORPORATION (VG) 2018-10-23 US disclosed
US-9676218-B2 Heat sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2017-06-13 US disclosed
US-20150367664-A1 HEAT SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2015-12-24 US disclosed
EP-1645430-B1 METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2011-11-30 EP disclosed
US-20110217544-A1 ENHANCED SURFACES, COATINGS, AND RELATED METHODS INNOVA DYNAMICS, INC. (US) 2011-09-08 US disclosed
EP-2328731-A1 ENHANCED SURFACES, COATINGS, AND RELATED METHODS Innova Dynamics, Inc. (US) 2011-06-08 EP disclosed
EP-1645430-A1 METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR THERMAL RECORDING ARTICLE AND THERMAL RECORDING ARTICLE Sanko Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20030207787-A1 Composition capable of indicating by color change when consumer articles, particularly volatile material dispensers, containing or associated with the composition have become inefficient in use. The composition includes:a volatile and FIRMENICH SA (CH) 2003-11-06 US disclosed
EP-1342081-A2 COMPOSITIONS ABLE TO INDICATE WHEN THEY BECOME INEFFICIENT IN USE Firmenich S.A. (CH) 2003-09-10 EP disclosed
US-20020110498-A1 Compositions able to indicate when they become inefficient in use FIRMENICH SA (CH) 2002-08-15 US disclosed
WO-2002046743-A2 COMPOSITIONS ABLE TO INDICATE WHEN THEY BECOME INEFFICIENT IN USE FIRMENICH S.A. (CH) 2002-06-13 WO disclosed
US-5501945-A Method of using multichromic polymers in packaging THE UNIVERSITY OF AKRON (US) 1996-03-26 US disclosed
EP-0349194-A2 Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-01-03 EP disclosed