SCHEMBL1728542

SCHEMBL1728542

Cc1c(N)cc2c(c1C)C(c1ccc(N(C)C)cc1)(c1ccn(C)c1)OC2=O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
HIF1A Q16665 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL302269 0.89 MEN1 (0.57) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL1727670 0.82 MEN1 (0.50) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL31715255 0.81 ALDH1A1 (0.42) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL10434322 0.80 TDP1 (0.57) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL1446856 0.78 ALDH1A1 (0.76) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL29791059 0.78 ALDH1A1 (0.76) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL11041419 0.78 MEN1 (0.51) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL10434310 0.75 MEN1 (0.48) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL7764773 0.75 ALDH1A1 (0.43) MEN1KMT2AALDH1A1CYP3A4HPGD
SCHEMBL10434290 0.75 MEN1 (0.50) MEN1KMT2AALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1645430-B1 METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2011-11-30 EP disclosed
US-20090233246-A1 METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR THERMAL RECORDING ARTICLE AND THERMAL RECORDING ARTICLE ODA SHIGERU 2009-09-17 US disclosed
US-7557065-B2 Method for producing material containing sensitizer dispersed therein for thermal recording article and a thermal recording article SANKO CO., LTD. (JP) 2009-07-07 US disclosed
US-20060252645-A1 Method for producing material containing sensitizer dispersed therein for thermal recording article an thermal recording article SANKO CO., LTD. (JP) 2006-11-09 US disclosed
EP-1645430-A1 METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR THERMAL RECORDING ARTICLE AND THERMAL RECORDING ARTICLE Sanko Co., Ltd. (JP) 2006-04-12 EP disclosed