Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 4/20 | 0.41 |
| ▸ | UBE2M | P61081 | 7/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1448587 | 1.00 | CCR5 (0.41) | CCR5UBE2MDCUN1D1MCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1449812 | 0.99 | CCR5 (0.42) | CCR5UBE2MDCUN1D1MCHR1ALDH1A1 | |
| SCHEMBL1981093 | 0.96 | UBE2M (0.39) | CCR5UBE2MDCUN1D1MCHR1LMNA | |
| Hydrochloric Acid SCHEMBL842054 | 0.95 | CCR5 (0.40) | CCR5UBE2MDCUN1D1MCHR1LMNA | |
| SCHEMBL1981028 | 0.94 | UBE2M (0.42) | UBE2MDCUN1D1MCHR1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL843043 | 0.94 | UBE2M (0.41) | UBE2MDCUN1D1MCHR1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1449792 | 0.93 | CCR5 (0.42) | CCR5UBE2MDCUN1D1MCHR1ALDH1A1 | |
| SCHEMBL1983004 | 0.93 | MCHR1 (0.39) | CCR5UBE2MDCUN1D1MCHR1ALDH1A1 | |
| SCHEMBL842452 | 0.93 | MCHR1 (0.39) | CCR5UBE2MDCUN1D1MCHR1ALDH1A1 | |
| SCHEMBL1981333 | 0.93 | MCHR1 (0.43) | UBE2MDCUN1D1MCHR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143235-A1 | METHODS AND COMPOSITIONS FOR TREATING CYTOKINE STORM INFECTIONS, INCLUDING COVID-19, BY INHIBITING CCR5/CCL5 INTERACTION | IncellDx, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |