Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.91 |
| ▸ | CCR5 | P51681 | 12/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1053063 | 1.00 | KCNH2 (0.91) | KCNH2CCR5 | |
| SCHEMBL1079565 | 1.00 | KCNH2 (0.91) | KCNH2CCR5 | |
| SCHEMBL1198749 | 0.95 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL1080663 | 0.95 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL30227220 | 0.95 | KCNH2 (1.00) | KCNH2CCR5 | |
| Water SCHEMBL4012865 | 0.94 | KCNH2 (0.99) | KCNH2CCR5 | |
| SCHEMBL13719481 | 0.94 | CCR5 (0.91) | KCNH2CCR5 | |
| Water SCHEMBL4012863 | 0.94 | KCNH2 (0.99) | KCNH2CCR5 | |
| SCHEMBL3070604 | 0.93 | KCNH2 (1.00) | KCNH2CCR5 | |
| SCHEMBL3070606 | 0.93 | KCNH2 (1.00) | KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143235-A1 | METHODS AND COMPOSITIONS FOR TREATING CYTOKINE STORM INFECTIONS, INCLUDING COVID-19, BY INHIBITING CCR5/CCL5 INTERACTION | IncellDx, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |