Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227416 | 0.91 | CCR5 (0.80) | CCR5 | |
| SCHEMBL14434347 | 0.89 | CCR5 (0.81) | CCR5 | |
| SCHEMBL13326712 | 0.84 | CCR5 (0.81) | CCR5 | |
| SCHEMBL5237789 | 0.84 | CCR5 (0.81) | CCR5 | |
| SCHEMBL13326700 | 0.82 | CCR5 (0.82) | CCR5 | |
| SCHEMBL5422017 | 0.82 | CCR5 (0.82) | CCR5 | |
| SCHEMBL4692228 | 0.79 | CCR5 (0.77) | CCR5 | |
| SCHEMBL5233184 | 0.79 | CCR5 (1.00) | CCR5 | |
| SCHEMBL13326706 | 0.79 | CCR5 (1.00) | CCR5 | |
| SCHEMBL5418329 | 0.79 | CCR5 (1.00) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143235-A1 | METHODS AND COMPOSITIONS FOR TREATING CYTOKINE STORM INFECTIONS, INCLUDING COVID-19, BY INHIBITING CCR5/CCL5 INTERACTION | IncellDx, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |