Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 16/20 | 1.00 |
| ▸ | ICAM1 | P05362 | 16/20 | 1.00 |
| ▸ | ITGAL | P20701 | 16/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439738 | 1.00 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6439742 | 1.00 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6310919 | 0.83 | ITGB2 (0.71) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6310956 | 0.82 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310946 | 0.74 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL6308992 | 0.74 | ITGB2 (0.64) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6309030 | 0.74 | ITGB2 (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL6309016 | 0.68 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL6309561 | 0.65 | ITGB2 (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL7170389 | 0.65 | ITGB2 (0.75) | ITGB2ICAM1ITGALKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230107927-A1 | METHODS OF TREATING IATROGENIC AUTOIMMUNE COLITIS | FIRST WAVE BIO, INC. | 2023-04-06 | — | — | US | disclosed |