Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 11/20 | 0.64 |
| ▸ | ICAM1 | P05362 | 11/20 | 0.64 |
| ▸ | ITGAL | P20701 | 11/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310919 | 0.88 | ITGB2 (0.71) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL6309030 | 0.84 | ITGB2 (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL6309016 | 0.77 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL6311580 | 0.76 | ITGB2 (0.42) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310956 | 0.75 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL6311938 | 0.75 | ITGB2 (0.40) | ITGB2ICAM1ITGAL | |
| SCHEMBL30227629 | 0.74 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6439742 | 0.74 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6439738 | 0.74 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6311802 | 0.73 | SLC6A1 (0.41) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |