Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.70 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.70 |
| ▸ | ITGAL | P20701 | 19/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309030 | 0.88 | ITGB2 (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310946 | 0.85 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310919 | 0.84 | ITGB2 (0.71) | ITGB2ICAM1ITGAL | |
| SCHEMBL6439742 | 0.82 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL30227629 | 0.82 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL6439738 | 0.82 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL6317156 | 0.80 | ITGB2 (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL6309016 | 0.78 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL6309616 | 0.76 | ITGAL (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL6570025 | 0.76 | ITGAL (0.54) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |