Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 8/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228019 | 0.93 | CA12 (0.41) | KCNA3CA9CA12ESR1ESR2 | |
| SCHEMBL30228486 | 0.89 | KCNA3 (0.49) | KCNA3CA9CA12ESR1ESR2 | |
| SCHEMBL30227920 | 0.83 | KCNA3 (0.53) | KCNA3CA9CA12ARMAOB | |
| SCHEMBL30228351 | 0.81 | CA12 (0.43) | KCNA3CA9CA12ESR1ESR2 | |
| SCHEMBL30228381 | 0.80 | KCNA3 (0.56) | KCNA3CA9CA12MAOBNPC1 | |
| Hydrochloric Acid SCHEMBL30228355 | 0.78 | KCNA3 (0.55) | KCNA3CA9CA12MAOBNPC1 | |
| SCHEMBL30228517 | 0.77 | KCNA3 (0.54) | KCNA3CA9CA12MAOBNPC1 | |
| SCHEMBL30283853 | 0.76 | ROCK1 (0.39) | ESR1ESR2 | |
| SCHEMBL30228231 | 0.76 | KCNA3 (0.53) | KCNA3CA9CA12MAOBNPC1 | |
| SCHEMBL31710481 | 0.75 | KCNA3 (0.52) | KCNA3CA9CA12MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |