Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228486 | 0.85 | KCNA3 (0.49) | KCNA3RAB9AMAOBNPC1MAOA | |
| SCHEMBL30228381 | 0.85 | KCNA3 (0.56) | KCNA3RAB9AMAOBNPC1MAOA | |
| Hydrochloric Acid SCHEMBL30228355 | 0.84 | KCNA3 (0.55) | KCNA3RAB9AMAOBNPC1MAOA | |
| SCHEMBL30228109 | 0.83 | KCNA3 (0.47) | KCNA3RAB9AMAOBNPC1MAOA | |
| SCHEMBL30228517 | 0.83 | KCNA3 (0.54) | KCNA3RAB9AMAOBNPC1MAOA | |
| SCHEMBL30228194 | 0.82 | KCNA3 (0.48) | KCNA3RAB9ACA9CA12MEN1 | |
| SCHEMBL30228231 | 0.82 | KCNA3 (0.53) | KCNA3RAB9AMAOBNPC1MAOA | |
| SCHEMBL30228654 | 0.82 | KCNA3 (0.44) | KCNA3RAB9AMAOBNPC1MAOA | |
| SCHEMBL31710481 | 0.81 | KCNA3 (0.52) | KCNA3RAB9AMAOBMAOATDP1 | |
| SCHEMBL30231784 | 0.80 | KDM4E (0.67) | KCNA3RAB9ANPC1MAOACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |