Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227998 | 0.89 | SMN1; SMN2 (0.44) | CA12CA9ESR1MEN1KMT2A | |
| SCHEMBL31710928 | 0.89 | SMN1; SMN2 (0.44) | CA12CA9ESR1MEN1KMT2A | |
| SCHEMBL30227990 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL30228304 | 0.85 | DPP4 (0.45) | DPP4DPP7CA12CA9ESR1 | |
| SCHEMBL30228393 | 0.85 | DPP4 (0.45) | DPP4DPP7CA12CA9ESR1 | |
| SCHEMBL30228318 | 0.85 | DPP4 (0.45) | DPP4DPP7CA12CA9ESR1 | |
| SCHEMBL30228300 | 0.84 | MEN1 (0.42) | CA12CA9ESR1MEN1KMT2A | |
| SCHEMBL30228487 | 0.83 | CA12 (0.40) | DPP4DPP7CA12CA9ESR1 | |
| SCHEMBL30228254 | 0.80 | DPP4 (0.44) | DPP4DPP7CA12CA9MEN1 | |
| SCHEMBL20848082 | 0.78 | ALDH1A1 (0.54) | DPP4DPP7MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |