Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228398 | 0.87 | NPC1 (0.51) | KCNA3NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL30228438 | 0.86 | KCNA3 (0.59) | KCNA3CA9CA12NPC1RAB9A | |
| SCHEMBL30227982 | 0.86 | KCNA3 (0.55) | KCNA3CA9CA12ALDH1A1KMT2A | |
| SCHEMBL30228013 | 0.83 | MAPK14 (0.49) | KCNA3NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30228546 | 0.82 | KCNA3 (0.52) | KCNA3CA9CA12ALDH1A1KMT2A | |
| SCHEMBL30228312 | 0.79 | KCNA3 (0.46) | KCNA3CA9CA12NPC1RAB9A | |
| SCHEMBL22431749 | 0.79 | CA12 (0.70) | KCNA3CA9CA12ALDH1A1KMT2A | |
| SCHEMBL30228248 | 0.79 | CA12 (0.70) | KCNA3CA9CA12ALDH1A1KMT2A | |
| SCHEMBL30228274 | 0.78 | CA12 (0.70) | KCNA3CA9CA12NPC1RAB9A | |
| SCHEMBL30228412 | 0.76 | KCNA3 (0.62) | KCNA3CA9CA12RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |