Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227943 | 0.84 | CA12 (0.45) | KDM4ESMN1; SMN2CA12CA9ALOX5 | |
| SCHEMBL30228052 | 0.84 | CA12 (0.48) | KDM4ESMN1; SMN2CA12CA9ALOX5 | |
| SCHEMBL30228086 | 0.84 | CA12 (0.43) | KDM4ESMN1; SMN2CA12CA9ALOX5 | |
| SCHEMBL30228122 | 0.81 | HPGD (0.40) | KDM4ESMN1; SMN2CA12CA9ALOX5 | |
| SCHEMBL30228226 | 0.80 | CA12 (0.69) | KDM4ECA12CA9HSD17B3ESR1 | |
| SCHEMBL30228096 | 0.80 | CA12 (0.48) | KDM4ECA12CA9MEN1KMT2A | |
| SCHEMBL20839408 | 0.80 | CA12 (0.69) | KDM4ECA12CA9HSD17B3ESR1 | |
| SCHEMBL30228300 | 0.79 | MEN1 (0.42) | KDM4ESMN1; SMN2CA12CA9ALOX5 | |
| SCHEMBL30228049 | 0.78 | PARP1 (0.45) | KDM4ESMN1; SMN2CA12CA9AR | |
| SCHEMBL30228177 | 0.78 | KDM4E (0.49) | KDM4ESMN1; SMN2CA12CA9HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |