Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227943 | 0.88 | CA12 (0.45) | CA12CA9ALOX5ESR1KDM4E | |
| SCHEMBL30228288 | 0.84 | KDM4E (0.47) | CA12CA9ALOX5ESR1KDM4E | |
| SCHEMBL30228086 | 0.84 | CA12 (0.43) | CA12CA9ALOX5ESR1KDM4E | |
| SCHEMBL20839408 | 0.83 | CA12 (0.69) | CA12CA9ESR1KDM4EALDH2 | |
| SCHEMBL30228226 | 0.83 | CA12 (0.69) | CA12CA9ESR1KDM4EALDH2 | |
| SCHEMBL30228300 | 0.82 | MEN1 (0.42) | CA12CA9ALOX5ESR1KDM4E | |
| SCHEMBL30228404 | 0.82 | CA12 (0.41) | CA12CA9ALOX5ESR1KDM4E | |
| SCHEMBL30228177 | 0.81 | KDM4E (0.49) | CA12CA9ESR1KDM4ESMN1; SMN2 | |
| SCHEMBL30228096 | 0.81 | CA12 (0.48) | CA12CA9KDM4EMAOBMEN1 | |
| SCHEMBL30227956 | 0.81 | CA12 (0.48) | CA12CA9ALOX5ESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |