Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227976 | 0.88 | KCNA3 (0.48) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL30228317 | 0.87 | KCNA3 (0.47) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL30228319 | 0.87 | KCNA3 (0.47) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL30228192 | 0.85 | KCNA3 (0.46) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL30228296 | 0.85 | KCNA3 (0.46) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL30227924 | 0.82 | KCNA3 (0.46) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL20839098 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL30227928 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL30227927 | 0.81 | HSD17B10 (0.42) | ALDH1A1KDM4EHTTKCNA3IGLV6-57 | |
| SCHEMBL31710481 | 0.78 | KCNA3 (0.52) | ALDH1A1KDM4ELMNAHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |