Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228235 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL30228290 | 0.84 | MAOB (0.49) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL30228274 | 0.82 | CA12 (0.70) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL31710488 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL30228426 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL30228340 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL30228217 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL30228334 | 0.79 | RAB9A (0.60) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL30228065 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNAL3MBTL1KCNA3RAB9A | |
| SCHEMBL22431636 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAKCNA3RAB9ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |