Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31710963 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30228046 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL31711268 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30228062 | 0.91 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30228133 | 0.89 | KCNA3 (0.42) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28897248 | 0.84 | CYP3A4 (0.41) | ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL28438857 | 0.84 | CYP3A4 (0.41) | ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL28434585 | 0.84 | CYP3A4 (0.41) | ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL28440360 | 0.84 | CYP3A4 (0.41) | ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL31710619 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |